Caspian Journal of Veterinary Sciences

Caspian Journal of Veterinary Sciences

A review of the risk of acrylamide in food products

Document Type : Review article

Authors
1 Department of Nutritional Sciences, School of Health, Golestan University of Medical Sciences, Gorgan, Iran.
2 Food, Drug and Natural Products Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
3 Department of Pathobiology, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran.
Abstract
Acrylamide (C3H5NO) is a white crystal which is soluble in water as well as ethanol, ether, and chloroform. It is degraded after exposing to acidic and alkaline substances, oxidizing agents, iron, and salt. Nowadays, acrylamide is produced to prepare polyacrylamide which is widely used in wastewater treatment and paper, textile, coatings, and dyes industries, etc. Regarding food safety viewpoint, risk assessment of this toxin in foods seems to be essential. On the other hand, lack of standard inspection laws and surveillance on traditional foods, especially those prepared in restaurants and street vendors, is a main concern. Therefore, the main purpose of this study was to review acrylamide risk in food products. Despite the importance of prevention against acrylamide production in high-risk food before or during the cooking process, it sometimes seems to be difficult to achieve this goal. Therefore, developing effective strategies to inform and educate consumers to reduce hazardous food intake or use of effective compounds to reduce acrylamide toxicity in body are of practical approaches. Medicinal plants containing polyphenols and antioxidants reduce acrylamide production through the interaction between sugars and asparagine amino acids. Also, it has been shown that some antioxidant plant compounds reduce the toxicity of chemical hazards (such as acrylamide) in the body of humans and animals.
Keywords
Subjects

Anese, M; Suman, M and Nicoli, MC (2009). Technological strategies to reduce acrylamide levels in heated foods. Food Eng. Rev., 1: 169-179.
Bahadar, H; Abdollahi, M; Maqbool, F; Baeeri, M and Niaz, K (2014). Mechanistic overview of immune modulatory effects of environmental toxicants. Inflamm. Allergy Drug Targets. 13: 382-386.
Boroushaki, MT; Nikkhah, E; Kazemi, A; Oskooei, M and Raters, M (2010). Determination of acrylamide level in popular Iranian brands of potato and corn products. Food Chem. Toxicol., 48: 2581-2584.
Chen, F;, Yuan, Y; Liu, J; Zhao, G and Hu, X (2008). Survey of acrylamide levels in Chinese foods. Food Addit. Contam., 1: 85-92.
Forstova, V; Belkova, B; Riddellova, K; Vaclavik, L; Prihoda, J and Hajslova, J (2014). Acrylamide formation in traditional Czech leavened wheat-rye breads and wheat rolls. Food Control. 38: 221-226.
Franeka, M; Rubio, D; Diblikova, I and Rubio, F (2014). Analytical evaluation of a high-throughput enzyme-linked immunosorbent assay for acrylamide determination in fried foods. Talanta. 123: 146–150.
Gündüz, BCP and Cengiz, MF (2015). Acrylamide contents of commonly consumed bread types in Turkey. Int. J. Food Properties, 18: 833-841.
Hashemi, S; Ehrampoush, MH; Jalili, M; Limaki, SK and Hajimohammad, B (2020). Discrimination of sensorial characteristics, fungal, and aflatoxin B1 contamination of pistachio kernels after E-beam irradiation. Int. J. Env. Health Eng., 2:1-5.
Institute of Standards and Industrial Research of Iran (ISIRI) (2010). Chips- Specifications and test methods. URL: http://www.isiri.gov.ir/Portal/file/?33917/3764.pdf. Assessed 30 September 2016.
Kahkeshani, N; Saeidnia, S and Abdollahi, M (2014). Role of antioxidants and phytochemicals on acrylamide mitigation from food and reducing its toxicity. J Food Sci. Technol., 52: 3169-3186.
Keramat, J; LeBail, A; Prost, C and Jafari, M (2011). Acrylamide in baking products: A review article. Food Bioprocess Techn., 4: 530-543.
Koh, BK (2006). Determination of acrylamide content of food products in Korea. J. Sci. Food Agri., 86: 2587–2591.
Komthong, P; Suriyaphan, O and Charoenpanich, J (2012). Determination of acrylamide in Thaiconventional snacks from Nong Mon market, Chonburi using GC-MS technique. Food Addit. Contam., 5: 20-28.
Mason, S; Arjmandtalab, S; Hajimohammadi, B; Arsanjani, AK; Karami, S; Sayadi, M and Oryan, A (2015). Aflatoxin M1 contamination in industrial and traditional yogurts produced in Iran. J. Food Qual. Hazards Control, 2: 11-14.
Mason, S; Hajimohammadi, B; Ehrampoush, MH; Khabiri, F and Soltani, M (2015). A survey on relationship between diet and urinary excretion of aflatoxin M1: A screening pilot study on Iranian population. J. Food Qual. Hazards Control, 2: 66-70.
Mason, S; Arjmandtalab, S; Hajimohammadi, B; Ehrampoush, M; Khosravi Arsanjani, A; Jahed Khaniki, G; Rahimzade A and Raeisi, M (2016). Reduction of aflatoxin M1 during production of Kashk, a traditional Iranian dairy product. J. Food Qual. Hazards Control, 3: 10–14.
Maqbool, F; Mostafalou, S; Bahadar, H and Abdollahi, M (2016). Review of endocrine disorders associated with environmental toxicants and possible involved mechanisms. Life Sci., 145: 265-273.
Mesías, M and Morales, FJ (2015). Acrylamide in commercial potato crisps from Spanish market: Trends from 2004 to 2014 and assessment of the dietary exposure. Food Chem. Toxicol., 81: 104-110.
Mojska, H; Gielecińska, I and Stoś, K (2012). Determination of acrylamide level in commercial baby foods and an assessment of infant dietary exposure. Food Chem. Toxicol., 50: 2722-2728.
Motaghi, MM; Ardebili, MS; Honarvar, M; Mehrabani, M and Baghizadeh, A (2012). Determination of acrylamide in selected types of iranian breads by SPME technique. J. Food Biosci. Technol., 2: 57-64.
Oracz Nebesny, E and Żyżelewicz, D (2011). New trends in quantification of acrylamide in food products. Talanta. 86: 23-34.
Oroian, M; Amariei, S and Gutt, G (2015). Acrylamide in Romanian food using HPLC-UV and a health risk assessment. Food Addit. Contam., 8: 136-141.
Pacetti, D; Gil, E; Frega, NG; Álvarez, L; Dueñas, P; Garzón, A and Lucci, P (2015). Acrylamide levels in selected Colombian foods. Food Addit. Contam., 8: 99-105.
Powers, SJ; Mottram, DS; Curtis, A and Halford, NG (2013). Acrylamide concentrations in potato crisps in Europe from 2002 to 2011. Food Addit. Contam., 30: 1493-1500.
Rufian-Henares, JA; Arribas-Lorenzo, G and Morales, FJ (2007). Acrylamide content of selected Spanish foods: survey of biscuits and bread derivatives. Food Addit. Contam., 24: 343-350.
Saeidi Asl, R; Iraji Far, M and Fahimdanesh, M (2014). Evaluation of acrylamide contents of potato crisps sold in Iranian markets. J Food Biosci. Technol., 4: 53-56.
Saeidnia, S and Abdollahi, M (2013a). Toxicological and pharmacological concerns on oxidative stress and related diseases. Toxicol. Appl. Pharmacol., 273: 442-455.
Saeidnia, S and Abdollahi, M (2013b). Antioxidants: friends or foe in prevention or treatment of cancer: The debate of the century. Toxicol. Appl. Pharmacol., 271: 49-63.
Shahrbabki, PE; Hajimohammadi, B; Shoeibi, S; Elmi, M; Yousefzadeh, A; Conti, GO; Ferrante, M; Amirahmadi, M; Fakhri, Y and Mousavi Khaneghah, A (2018). Probabilistic noncarcinogenic and carcinogenic risk assessments (Monte Carlo simulation method) of the measured acrylamide content in Tah-dig using QuEChERS extraction and UHPLC-MS/MS. Food Chem. Toxicol., 118: 361–370.
Shamla, L and Nisha, P (2014). Acrylamide in deepfried snacks of India. Food Addit. Contam., 7: 220-225.
Tekkeli, SEK; Önal, C and Önal, A (2012). A review of current methods for the determination of acrylamide in food products. Food Analyt. Methods, 5: 29-39.
Vinci, RM; Mestdagh, F and De Meulenaer, B (2012). Acrylamide formation in fried potato products–Present and future, a critical review on mitigation strategies. Food Chem., 133: 1138-1154.
Volume 2, Issue 2
December 2025
Pages 1-5

  • Receive Date 13 July 2025
  • Accept Date 01 August 2025